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Information × Registration Number 0224U032826, (0123U103505) , R & D reports Title Development of a portable system for express monitoring of the ratio of lactate and pyruvate in the blood for urgent needs of clinical diagnostics popup.stage_title Оптимізація конструкції біосенсорної системи та підбір оптимальних умов її функціонування для визначення співвідношення лактату і пірувату в крові. Head Soldatkin Oleksandr O., Доктор біологічних наук Registration Date 06-12-2024 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description1 The aim of the work is to develop a portable biosensor system based on amperometric platinum electrodes with immobilized enzymes (lactate oxidase and pyruvate toxdase) for measuring the ratio of lactate to pyruvate concentrations in the blood during medical diagnostics, in particular for clinical assessment of the severity of the condition of patients with polytrauma. popup.description2  Monobiosensors for the analysis of pyruvate and lactate were developed and combined into a single biosensor system. The effect of solution parameters on the operation of the biosensor system was investigated. The reproducibility of signals, operational stability and storage stability of this system were investigated. A method for the simultaneous determination of lactate and pyruvate concentrations was developed and tested. The developed biosensor system was tested and the correlation of the results with traditional methods was investigated. Product Description popup.authors Bakhmat Veronika A. Berketa Kseniia O. Karpenko Yurii V. Melnyk Volodymyr H. Mruha Daryna O. Sverstiuk Andrii S. Sobolevskyi Maksym S. Soldatkina Olha V. popup.nrat_date 2024-12-06 Close