Registration Number
0224U033135,
(0120U101550)
, R & D reports
Title
Medicamentous correction of metabolic and immunological disorders, intensity of systemic inflammation and endothelial dysfunction in patients with combined course of cardiovascular and bronchial obstructive diseases, lesions of the musculoskeletal system and chronic dermatoses
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Медикаментозна корекція метаболічних та імунологічних порушень, інтенсивності системного запалення та ендотеліальної дисфункції у пацієнтів з поєднаним перебігом серцево-судинних та бронхообструктивних захворювань, ураженням опорно-рухового апарату та хронічними дерматозами
Head
Ilashchuk Tetiana O., Доктор медичних наук
Registration Date
18-12-2024
Organization
Bukovinian State Medical University
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To study the features of the course and diagnosis of combined lesions of cardiovascular (coronary heart disease, arterial hypertension) and respiratory systems (COPD, bronchial asthma), musculoskeletal system, metabolic disorders (diabetes mellitus, obesity), chronic dermatoses, to develop the methods of medicamentous correction of these lesions by influencing the metabolic, immunological processes, indicators of systemic inflammation and endothelial dysfunction
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Improved diagnostic approaches have been developed for comorbid conditions, including the following: arterial hypertension combined with osteoarthritis; rheumatoid arthritis with chronic coronary syndrome; ischemic heart disease paired with chronic obstructive pulmonary disease (COPD); and asthma-COPD overlap syndrome accompanied by type 2 diabetes mellitus. These improvements are based on a comprehensive analysis and assessment of changes in clinical-hemodynamic, metabolic, and biochemical characteristics. Additionally, treatment technologies have been optimized for patients with chronic dermatoses, including allergic dermatoses, psoriasis, lichen planus, and rosacea. The optimization considers the clinical manifestations of these skin conditions, the status of the hepatobiliary system, and the intestinal microbiota. The comprehensive therapy includes the use of angioprotective, hepatoprotective, and enzymatic agents, along with a multiprobiotic.
Product Description
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Ilashchuk Tetiana O.
Bachuk-Ponych Nataliia V.
Bobkovych Kateryna O.
Brodovska Nadiia B.
Vasyuk Valentyna L.
Haievska Maryna Yu.
Halytska Valeriia O.
Hlubochenko Olena V.
Hovornian Anastasiia V.
Olha I. Denysenko
Doholich Oleksandra I.
Lukashevych Inna V.
Mikulets Liudmyla V.
Mykytiuk Oksana P.
Okipniak Iryna V.
Perepichka Mykhailo P.
Vasyl P. Prysiazhniuk
Seniuk Bohdana P.
Storozhuk Maryna V.
Stupnytska Hanna Ya.
Tashchuk Maksym V.
Fedoruk Viktoriia O.
Shevchuk Mykola M.
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2024-12-19