Registration Number
0224U033143,
(0120U102805)
, R & D reports
Title
New technologies for diagnosis and pathogenetic treatment of proximal nephron dysfunction under the conditions of development of systemic and renal classical and dysregulatory pathological processes
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Нові технології діагностики та патогенетичного лікування дисфункції проксимального відділу нефрона за умов розвитку системного і ниркового класичного та дизрегуляційного патологічних процесів
Head
Rohovyi Yurii Ye., Доктор медичних наук
Registration Date
19-12-2024
Organization
Bukovinian State Medical University
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Development of new methods of treatment of proximal nephron dysfunction, urinary sodium ion loss syndrome, glomerular-tubular, tubular-tubular balance disorders and tubulo-glomerular feedback under conditions of development of systemic and renal classical and dysregulatory pathological processes.
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Improved methods for the diagnosis, treatment, and prevention of proximal nephron dysfunction and sodium loss syndrome in relation to disorders of glomerulo-tubular, tubulo-tubular balance, and tubulo-glomerular feedback have been developed. These methods involve the use of antioxidants, cytoprotectors, negative redox potential, and molecular hydrogen under conditions of systemic and renal classical and dysregulation pathological processes. New data have been obtained regarding the pathogenesis of the effects of a solution with a negative redox potential saturated with molecular hydrogen on functional and biochemical processes in the kidneys under conditions of moderate acute hemic hypoxia. This includes insights into impaired oxidation and phosphorylation, the no-reflow syndrome at the early polyuric stage of mercuric nephropathy under a hyponatremic diet, and irritable bowel syndrome with constipation and diarrhea.
Product Description
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Bilookyi Viacheslav V.
Doroshko Volodymyr A.
Kolesnik Oksana V.
Lisnianska Nataliia V.
Perepeliuk Mariia D.
Rohovyi Yurii Ye.
Slobodian Kseniia V.
Khodorovskyi Volodymyr M.
Tsytrin Volf Ya.
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2024-12-19
