Registration Number
0224U033209,
(0120U101512)
, R & D reports
Title
Clinical and experimental substantiation of optimization of the prevention methods and treatment of special complications in surgery practice and intensive therapy
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Клінічне та експериментальне обґрунтування оптимізації методів профілактики та лікування окремих ускладнень в хірургічній практиці та інтенсивній терапії
Head
Konovchuk Viktor M., Доктор медичних наук
Registration Date
21-12-2024
Organization
Bukovinian State Medical University
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To improve the results of treatment of the patients suffering from diabetes mellitus with pioseptic complications by means of elaboration of early diagnostics of the origin of critical ischemia disorders of the lower extremities and substantiation of optimization of methods of their treatment
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Studies have shown that in patients with type 2 diabetes, endothelial dysfunction in the diabetic foot includes a violation of the physiological regulation of vascular homeostasis due to insufficient release of endothelium-dependent factors of relaxation and vasoconstriction of vessels. The prognostic value of lowering the skin temperature of the sole of the foot in patients with diabetes mellitus as a risk factor for the development of purulent-necrotic complications was established. When studying the spectral dependence of the optical density of the venous blood plasma on the measurement wavelength, it was found that at a wavelength of λ=280 nm, the maximum value of the optical density occurs in children with peritonitis, which corresponds to the beginning of the formation of adhesions in the abdominal cavity. This makes it possible to predict the development of the adhesion process in the abdominal cavity. It was established that the course of chronic maxillary sinusitis with type 1 diabetes mellitus is accompanied by dysbiosis, which justifies the need to assess the state of impaired microbiocenosis of mucous membranes in patients with this pathology.
Product Description
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Akentiev Serhii O.
Andruschak Andrii V.
Oleh B. Bodnar
Vatamanesku Livii I.
Kalutskyi Ihor V.
Kyfiak Petro V.
Konovchuk Viktor M.
Kushnir Serhii V.
Levytska Svitlana A.
Mazur Olha O.
Malaiko Serhii S.
Nechytailo Olena Yu.
Petrynych Volodymyr V.
Plaksyvyi Oleksandr H.
Sapunkov Oleh D.
Sokolnyk Serhii O.
Tkachuk Oleksii V.
Khashchuk Vasyl S.
Yakovets’ Karolina I.
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2024-12-21