Registration Number
0225U000471,
(0122U001457)
, R & D reports
Title
Molecular mechanisms of adaptation to stress and search for natural adaptogens
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Молекулярні механізми адаптації до стресу та пошук природних адаптогенів
Head
Ushakova Halyna O., Доктор біологічних наук
Registration Date
12-01-2025
Organization
Oles Honchar Dnipro National University
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Identify possible molecular mechanisms of adaptation of human and animals to different types of stress and search for natural adaptogens to prevent complications of acute and chronic stress.
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The purpose of the work is to determine the features of the molecular mechanisms of human and animal adaptation to various types of stress and to search for natural adaptogens to prevent complications of acute and chronic stress. The object is the state of functional systems and molecular physiological and biochemical mechanisms of human and animal adaptation to acute and chronic stress and the influence of natural adaptogens. The subject is emotional and behavioral reactions, indicators of the cardiovascular system and blood, bioelectrical activity of the brain, astrocytes, myelin, biochemical indicators. In modern living conditions, the impact of stressors of various nature and duration on humans is growing uncontrollably. As a result, the activity of the regulatory systems of the body is disrupted and the number of pathologies of its functional systems is increasing: cardiovascular and blood, nervous, endocrine, gastrointestinal. The question of the mechanisms of adaptive reactions of the body at different stages of the general adaptation syndrome, chronic stress, as well as its long-term consequences remains relevant. The search for adaptogens that would minimize the negative impact of stress factors and prevent complications of stress is ongoing.
Product Description
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Horila Maryna V.
Domshyna Olha O.
Severynovska Olena V.
Skoryk Olena D.
Ushakova Halyna O.
Khomenko Olena M.
Shсherbyna Tetiana V.
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2025-01-12
