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Information × Registration Number 0225U001365, (0124U001099) , R & D reports Title Application of regenerative medicine technologies for the treatment of chronic wounds popup.stage_title Дослідження ефективності застосування ацелюлярного матриксу шкіри для лікування хронічних ран. Виділення, аналіз та кріоконсервація екзосом із стовбурових клітин. Head Oksana O. Shevchuk, Доктор медичних наук Registration Date 30-01-2025 Organization Ternopil National Medical University named after I. Gorbachevsky of the Ministry of Health of Ukraine popup.description1 To investigate the pathophysiological and pathobiochemical characteristics of chronic wound healing when using cellular and acellular regenerative medicine technologies. popup.description2  Research report: 72 p., 18 fig., 1 table., 136 sources MESENCHYMAL STEM CELLS; CELL CULTURES; CHRONIC WOUND; WOUND HEALING PROCESS; RATS, HISTOLOGICAL ANALYSIS Object of the study: chronic wound; wound healing process; effectiveness of the use of acellular skin matrix. Purpose of the work: to study the pathophysiological and pathobiochemical features of chronic wound healing when using cellular and acellular technologies of regenerative medicine. Research methods: preclinical - modeling of a full-thickness wound in pigs, modeling of a muscular-aponeurotic defect of the abdominal wall in rats; laboratory - histological, morphometric, histochemical, cytofluorimetric, cytogenetic studies (karyotyping) of the obtained MSCs; cell cultivation, spectrophotometry, lyophilization, statistical analysis of the obtained results. Product Description popup.authors popup.nrat_date 2025-01-30 Close