Registration Number
0225U002160,
(0122U000336)
, R & D reports
Title
Investigate the features of diagnosis, clinic and surgical treatment of embryonic brain tumors in young children
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Дослідити особливості діагностики, клініки та хірургічного лікування ембріональних пухлин головного мозку у дітей молодшого віку
Head
Verbova Liudmyla М., Доктор медичних наук
Registration Date
21-02-2025
Organization
The State Institution "Romodanov Neurosurgery Institute, National Academy of Medical Sciences of Ukraine"
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To improve the results of treatment of young children with embryonic brain tumors by substantiating and developing a differential approach to surgical combination treatment based on the analysis of anatomical and topographic, histomorphological features of tumors and the results of surgical treatment of this category of patients
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The report on the GDR is complete, laid out on 56 pages of printed text, illustrated with 32 figures, 13 tables, and 68 reference sources are used.
YOUNG CHILDREN, BRAIN TUMORS, EMBRYONIC TUMORS.
Scientific novelty Analysis of the clinical picture of the disease, the results of neuroimaging methods of diagnosis allows to determine adequate surgical tactics in children of younger age with embryonic brain tumors, which in turn will improve the results and reduce the mortality rate; Determining the mechanisms of cooperation of certain proteins helps to determine morphogenetic and pathohistological signs, which can be useful for predicting the course of the disease; The biological properties of embryonic brain tumors in young children were studied on clinical material; The conducted analysis comparing the results of the clinical diagnostic study of children with embryonic brain tumors with the results of surgical treatment will allow to develop indications and contraindications for carrying out various types of surgical treatment
Practical significance The study of anatomical topographical features of embryonic brain tumors in young children and the results of molecular and histological studies makes it possible to make a significant contribution to the development of childhood neuro-oncology, and to its separate, difficult division, neuro-oncology of young children age, infants and children under three years of age. The obtained results of neuroimaging diagnostic methods will allow more correct planning of surgical treatment of the specified category of patients; The conducted analysis of surgical treatment of young children with embryonic brain tumors allows to more clearly formulate indications and contraindications for surgery; Analysis of the immediate results of treatment of patients with the specified pathology allows to identify postoperative complications, which will contribute to the development of methods of their prevention.
Product Description
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Verbova Liudmyla M.
Malysheva Tetiana A.
Marushchenko Leonid L.
Molodetskyi Oleksandr M.
Plavskyi Mykola V.
Protsenko Ivan P.
Chuvashova Olha Yu
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2025-02-21
