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Information × Registration Number 0225U002497, (0122U002258) , R & D reports Title Determination of radiogenic risks of mortality of participants in the liquidation of the Chornobyl accident consequences in 1986-1987 and the adult population of radioactively contaminated areas of Ukraine from major non-neoplastic diseases on the basis of cohort epidemiological studies for the period 1988-2021. popup.stage_title Аналітичний аналіз та оцінка радіогенних ризиків смертності дорослого постраждалого населення, яке зазнало впливу іонізуючого випромінювання внаслідок аварії на ЧАЕС. Період аналізу 1988–2021 рр. Head Fedirko Pavlo A., Доктор медичних наук Registration Date 17-03-2025 Organization State Institution "National Research Center for Radiation Medicine, Hematology and Onkology of the National Academy of Medical Sciences of Ukraine" popup.description1 Based on descriptive analysis determine post-accident changes of the level and structure of mortality of LNA participants at the Chernobyl 1986-1987.  Period of epidemiological research and analysis 1988-2021 popup.description2  The overall mortality rate of CEW from non-tumor diseases tends to increase. The results of the risk analysis of dose dependence of mortality in the CEW cohort showed a higher sensitivity to ionizing radiation of the younger age group (18-39 years old at the date of the accident). The most dangerous period of the relative dose-dependent risk of death of CEW from non-cancerous diseases was established: 6-10 years after radiation exposure for all dose subgroups (from 0.05 Gy to 0.7 Gy) relative to the subgroup with an exposure dose of ˂ 0.05 Gy. Mathematical models were obtained that demonstrate the dynamics of the risk of mortality of CEW at the Chornobyl NPP from diseases of the circulatory system, digestive and respiratory organs. Significantly higher relative risks of mortality from certain diseases of the residents of the RCA with accumulated effective internal and external doses of more than 13 mSv were established compared to mortality rates in the subgroup with a dose of < 13 mSv. The most frequent causes of death were diseases of the musculoskeletal system and connective tissue, certain diseases of the circulatory system (pulmonary heart and pulmonary circulatory disorders, cardiomyopathy), and consequences of cerebrovascular diseases. The relative risks of mortality were significantly higher in the subgroup with a dose of 13-< 26 mSv in the period 21-30 years after the accident; in the subgroup with a dose of 26-< 50 mSv in the periods 6-15 years and 21-30 years after the accident; in the subgroup with a dose of ≥ 50 mSv in the periods 16-20 and 26-30 years after the accident compared to the mortality rates in the comparison subgroup. Product Description popup.authors Bieliaiev Yurii M. Babenko Tetiana F. Bohomolova Viktoriia V. Hubina Iryna H. Dorichevska Raisa Yu. Kapustynska Olha A. Kortushin Hennadii I. Levytska Iryna V. Prykashchykova Kateryna Ye. Rosokha (Yefimova) Yuliia V. Tereshchenko Serhii O. popup.nrat_date 2025-03-17 Close