Registration Number
0225U003082,
(0117U001281)
, R & D reports
Title
The fundamental bases of creation of fluorescent organic dyes for medical diagnostics, display elements and photonic devices
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Фундаментальні основи створення органічних барвників для флуоресцентної медичної діагностики, дисплейних елементів та фотонних пристроїв
Head
Tatarets Anatolii L.,
Registration Date
15-05-2025
Organization
State Scientific Institution Scientific and Technological Complex" Institute of Single Crystals "of the National Academy of Sciences of Ukraine
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The aim of the work was to establish general principles for the creation of fluorescent and dichroic dyes and hybrid organoinorganic nanoparticles, to study their combinations with biomolecules and liquid crystal materials for further application in medical diagnostics and thin-film display elements.
As a result of the project, the most promising classes of fluorescent and dichroic dyes were selected for use in different spectral regions. Methods for the synthesis and purification of rhodamine, cyanine and squaraine dyes and luminophors with different amounts of sulfonate and phosphonate groups were developed and improved. Regularities have been established regarding the relationship between the spectral luminescent and photoorienting properties of squaraine and norsquaraine dyes, chromene derivatives (xanthene dyes), rhodamines and violanthrones with their molecular and supramolecular structure, with covalent and non-covalent binding to proteins and with changes in pH in environments close to the conditions of living organisms. FRET between two dyes with absorption in different spectral regions has been studied, and the possibility of using such a FRET pair to determine conformational changes in proteins has been assessed. Semiconductor quantum rods with a combined "rod in rod" structure have been created without a negative effect on the optical properties of the resulting structure. It has been shown that the use of promesogenic dendritic ligands in combination with relatively short alkylphosphonic acids as a "cell" for distributing quantum rods in a liquid crystal monomer provides the highest optical quality and the absence of aggregation of quantum rods even at high concentrations. Polymerization of a liquid crystal monomer with quantum rods distributed in it has produced high-quality films for increasing the brightness of liquid crystal displays.
Product Description
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Biziaieva Yuliia V.
Burenkov Ivan O.
Vashchenko Valerii V.
Vlasenko Hanna S.
Hovor Iryna V.
Kaidash Mariia B.
Kobzev Dmytro V.
Kolosova Olha S.
Kryvoshei Oleksandr I.
Kulyk Olesia H.
Mykhailenko Vadym V.
Obukhova Olena M.
Popova Kateryna V.
Prodanov Maksym F.
Sаnin Eduаrd V.
Svoiakov Rostyslav Р.
Semenova Olha M.
Starko Serhii M.
Stepanenko Olena Yu.
Tatarets Anatolii L.
Fedoriako Oleksandr P.
Fediuniaieva Iryna A.
Khabuseva Saniia U.
Chernyshova Oksana S.
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2025-05-15
