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Information × Registration Number 0225U003850, (0123U100574) , R & D reports Title Concepts of mathematical modeling of molecular mechanisms of carcinogenesis popup.stage_title Концепції математичного моделювання молекулярних механізмів канцерогенезу Head Zaitseva Olha V., д.б.н. Registration Date 02-09-2025 Organization Kharkiv National Medical University popup.description1 Creation of probabilistic mathematical models and stochastic models of the processes occurring in tumor cells during malignization, promotion and progression, on the basis of a new study of the molecular mechanisms of the carcinogenesis process and its quantitative characteristics popup.description2  Methodological aspects of the study of molecular mechanisms of carcinogenesis are analyzed. A comparative characteristic of methods for constructing probabilistic models in biology and medicine is carried out. A stochastic model of the interaction of cancer cells and healthy tissue cells is created in the form of a stochastic differential equation in the sense of Ito and in the sense of Stratonovich and the corresponding Fokker-Planck-Kolmogorov equation for the transition density of the probability distribution. A method for processing and analyzing data from luminescent analysis of blood serum for the diagnosis of pathological and pre-pathological states of cancer patients is developed. A model of molecular mechanisms for the formation of hormetic reactions of biological objects to low-dose liquid ionizing radiation in the aspect of radiation therapy of cancer patients is proposed. Product Description popup.authors Bezkorovaina Viktoriia M. Bondarenko Maryna A. Ponomarenko Natalia S. Radzishevska Yevheniia B. Rysovana Liubov M. Solodovnikov Andrii S. popup.nrat_date 2025-09-02 Close