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Information × Registration Number 0226U001739, (0121U108881) , R & D reports Title 624. The role of cellular and tissue metabolism in the diagnosis, clinical course and treatment of renal and genital diseases popup.stage_title Оцінка заходів запобіжного впливу на прогресування захворювань нирок, сечових шляхів та статевих органів з обґрунтуванням принципової стратегії в лікуванні патологічних станів на підставі вивчення закономірностей їх перебігу. Head Kostiev Fedir I., д.мед.н. Registration Date 30-01-2026 Organization Odessa National Medical University popup.description1 To increase the effectiveness of prognosis, diagnosis and treatment of diseases of the kidneys, urinary tract and genitals by comprehensive study and justification of the role of cellular and tissue metabolism in the development of pathological processes and the possibility of preventing their progression based on clinical observations and experimental models. popup.description2 The following original model of bladder cancer in mini-pigs was developed and 34 new chemical compounds from the hydrazone group, which exhibit contractile and antispasmodic effects, were screened. All compounds were synthesized by the author's team with leading specialists, and their pharmacological effect on the small intestine segment used to form the artificial bladder reservoir was evaluated. The study also includes a preliminary analysis of oncological efficacy indicators of adjuvant hyperthermic intravesical chemotherapy in patients with non-muscle-invasive bladder cancer. Product Description popup.authors Yurii M. Dekhtiar Ruslan V. Savchuk Serhii O. Borysov Olena O. Yakymenko Denys M. Sebov Serhii V. Bohatskyi Roman S. Chystiakov Vsevolod A. Poliakov Kiril Y. Vydrin Oleksandr V. Rudenko Fedir I. Kostiev popup.nrat_date 2026-01-30 Close