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Information × Registration Number 0226U003582, (0123U101030) , R & D reports Title Scientific substantiation of safe levels of contamination with toxic metals of human biological environments according to the criteria of maladaptation of the population and those working in the conditions of hostilities in Ukraine popup.stage_title Інформаційний пошук, аналіз та узагальнення даних літератури з моніторингу виробничого середовища та довкілля, з біомоніторингу токсичних металів та есенційних мікроелементів; вивчення прийнятих у світі моделей біомоніторингу та оцінки ризиків впливу токсичних металів на з урахуванням вимог національних та міжнародних програм (WHO, EFSA, UNEP Chemicals, US ЕРА, FDA). Head Iryna M. Andrusyshyna, Доктор біологічних наук Registration Date 20-04-2026 Organization Kundiev Institute of Occupational Health of the National Academy of Medical Sciences of Ukraine popup.description1 substantiate the optimal levels of toxic metals and essential trace elements in biological environments (whole blood and hair) and assess the risks of increasing environmental pollution due to military weapons and assess the adaptation and maladaptation of the human body, identify risks of adverse effects and justify preventive measures. popup.description2 Research report: 110 pages, 26 tables, 11 figures, 140 sources TOXIC METALS, ESSENTIAL MICROELEMENTS, OPTIMAL CONTENT LEVELS, OCCUPATIONAL AND ENVIRONMENTAL IMPACTS, BIOLOGICAL NORM The object of study is human biological environments (whole blood, blood serum, urine, and hair). The purpose of the work is to develop and implement methodological approaches to substantiate optimal levels of toxic metals and essential trace elements in human biological environments. Research methods — inductively coupled plasma optical emission spectrometry (ICP-OES), photometry, biochemical analyzers, mathematical statistics methods, questionnaires, and information scientific search. Based on the research, a comparative assessment of the body's exposure to toxic metals and essential trace elements in different age groups of the population and professional contingents and military personnel was carried out, which allowed important conclusions to be drawn. In particular, the authors of the research established the patterns of translocation of a number of toxic metals and essential trace elements from environmental objects into human biological environments. Regional, age, and gender differences in the content of toxic metals and essential trace elements in human biological environments were studied for the period 2020-2024. The implementation of the topic made it possible to assess the risks of increasing environmental pollution on the formation of pathology, particularly occupational pathology, as a result of military weapons, and to assess the peculiarities of adaptation and maladaptation of the human body. It is recommended to reduce the reference values for the content of Pb, Cd, As, and V in whole blood and Pb, Cd, Cr, Mn, and V in hair The latter will contribute to the improvement of early clinical and laboratory detection of deficiencies and excesses of toxic and essential trace elements in the body of the population and workers. Product Description popup.authors Iryna M. Andrusyshyna Hennadii Tkach Olha I. Khomenko Viktor M. Zinchenko Olena H. Lampeka popup.nrat_date 2026-04-20 Close