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Registration Number

0304U002878, 0103U008566 , R & D reports

Title

Influence of physic and chemical factors on structure and biological activity of lipopolysaccharides (endotoxins), PL spectra changes induced by modification of LPS structure.

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Вплив фізичних та хімічних факторів на структурні особливості і біологічну активність ліпополісахаридів (ендотоксинів), зміна спектрів люмінесценції при модифікації структурного складу ліпополісахаридів.

Head

Getsko Ostap,

Registration Date

27-12-2004

Organization

Institute of Semiconductor Physics of National Academy of Sciences of Ukrain

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Modifications have been studied in of the optical properties (scattering, luminescence spectra, excitation spectra) of extremely deluted solutionds of bacterial lipopolysaccharides (native and modified). A method has been proposed for identification of the structure and content of the lipopolysaccharides according to the optical properties of their solutions. The sensitive method of registration (photon counting) allowed us to monitor very deluted solutions (less than 0.001%). This can help to simulate behavior of the toxin in an actual biological medium, thereby observing its biological activity.

Product Description

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2020-04-03