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0410U005828,
к.мед.н.
02-11-2010
o
Endotelial dysfunction at inflammatory bowel diseases and its correction
Stoykevich Marina Valerjevna,
popup.head Filippov Yurij Alexandrovich
popup.opponent Решетілов Юрій Іванович
popup.opponent Скрипник Ігор Миколайович
Дисертаційна робота присвячена удосконаленню лікування хворих на хронічні запальні захворювання кишечнику на підставі визначення патогенетичної ролі ендотеліальної дисфункції у їх прогресуванні. Встановлено, що перебіг ХЗЗК у 88,5 % хворих на ХрК, 80,0 % - на НВК та у 62,5 % - на ХК супроводжується синдромом ендотеліальної дисфункції, яка характеризується зниженням ЕЗВД ПА, зростанням рівня VCAM-1 та вмісту циркулюючих десквамованих ендотеліоцитів. Вияленовлено зв'язок між дисфункцією ендотелію та активацією прооксидантної ланки окислювального гомеостазу, а також рівнем ендотоксемії у хворих на ХЗЗК.
2010-11-02
2020-04-04
Updated: 2025-12-14
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