Registration Number
2121U000829, Article
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Книга
Title
Allergic diseases and chronic Epstein-Barr virus infection: pathogenesis, diagnostic approaches and therapeutic tactics of patient management (AI translated)
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Зубченко Світлана Олександрівна
Zubchenko Svitlana O.
Zubchenko Svitlana Oleksandrivna
Zubchenko Svitlana O.
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01-01-2021
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Харківський національний університет імені В. Н. Каразіна
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https://ekhnuir.karazin.ua/handle/123456789/16391
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Харків : Хнаціональний університет імені В.Н. Каразіна
Description
Zubchenko S.O. Allergic diseases and chronic Epstein-Barr virus infection: pathogenesis, diagnostic approaches and therapeutic tactics of patient management. – Manuscript.
Thesis for obtaining a scientific degree of Doctor of Medical Sciences by specialty 14.03.08 “Immunology and Allergology”, V.N. Karazin Kharkiv National University of the Ministry of Education and Science of Ukraine, Kharkiv, 2021.
Regional features of sensitizing profile based on the multiplex determination of sIgE (ALEX-test) in patients with allergic diseases living in the western regions of Ukraine were identified and a comparative analysis was performed depending on the patients’ place of residence (Lviv and other oblasts of western Ukraine, urban / rural). Regional and molecular endotypes of different nosologies of allergic diseases were distinguished as well as threshold values of sensitization with regard to causative allergens. Molecular-prognostic models of personalized risk of persistent allergic diseases development (86.5%, p <0.001), intermittent allergic diseases (75.0%, p <0.01), BA (84.6%, p <0.001) have been identified for the patients with the active phase of EBV-infection.
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2026-04-13
