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Information × Registration Number 2121U006068, Article popup.category Thesis Title popup.author popup.publication 01-01-2021 popup.source_user Сумський державний університет popup.source https://essuir.sumdu.edu.ua/handle/123456789/87549 popup.publisher European Society of Cardiology Description Coronary artery disease (CAD) is one of the main cause of death in European countries. The mortality associated with CAD has been rising for the past 30 years in Central and Easten Europe (including Ukraine). It is known that atherosclerosis is the primary risk factor of CAD development and Matrix metalloproteinase-9 (MMP-9) is involved in all stages of atherosclerosis and thus may contribute to CAD aggravation. It is very important to find specific mechanisms of atherosclerosis progression, the impact of genetic and external factors which influence on the development of CAD in different populations. Therefore, the aim of this study was to investigate the influence of MMP-9 concentration and functional rs17576 single nucleotide polymorphism (SNP) on risk of CAD development in Ukrainian population. popup.nrat_date 2025-05-12 Close