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Інформація × Реєстраційний номер 2121U006068, Матеріали видань та локальних репозитаріїв Категорія Thesis Назва роботи Coronary artery disease association with serum concentration and genetic variation of MMP-9 in Ukrainian population Автор Дата публікації 01-01-2021 Постачальник інформації Сумський державний університет Першоджерело https://essuir.sumdu.edu.ua/handle/123456789/87549 Видання European Society of Cardiology Опис Coronary artery disease (CAD) is one of the main cause of death in European countries. The mortality associated with CAD has been rising for the past 30 years in Central and Easten Europe (including Ukraine). It is known that atherosclerosis is the primary risk factor of CAD development and Matrix metalloproteinase-9 (MMP-9) is involved in all stages of atherosclerosis and thus may contribute to CAD aggravation. It is very important to find specific mechanisms of atherosclerosis progression, the impact of genetic and external factors which influence on the development of CAD in different populations. Therefore, the aim of this study was to investigate the influence of MMP-9 concentration and functional rs17576 single nucleotide polymorphism (SNP) on risk of CAD development in Ukrainian population. Додано в НРАТ 2025-05-12 Закрити