Registration Number
2124U012903, Article
popup.category
Текст
Title
Dynamic indicators of acute respiratory diseases treatment in children after correction (AI translated)
popup.author
Horlenko Olesya M.
Pikina Iryna Yu.
Prylypko Lyubomyra B.
Kossey Gabriella B.
Roshko Ihor H.
Brych Valeriya V.
Kedyk Antonina V.
Горленко Олеся Михайлівна
Пікіна Ірина Юріївна
Коссей Габріелла Барнабашівна
Прилипко Любомира Богданівна
Брич Валерія Володимирівна
Кедик Антоніна Володимирівна
Horlenko Olesya M.
Pikina Iryna Yu.
Prylypko Lyubomyra B.
Kossey Gabriella B.
Roshko Ihor H.
Brych Valeriya V.
Kedyk Antonina V.
Horlenko Olesya Mykhailivna
Pikina Iryna Yuriivna
Kossei Habriella Barnabashivna
Prylypko Liubomyra Bohdanivna
Brych Valeriya Volodymyrivna
Kedyk Antonina Volodymyrivna
popup.publication
01-01-2024
popup.source_user
Ужгородський національний університет
popup.source
https://dspace.uzhnu.edu.ua/jspui/handle/lib/64242
popup.publisher
Description
Aim: To study the Respiratory pathology of the upper respiratory tract, markers of the inflammatory response of the organism, Oxidative stress, Metabolic
adaptation and possibilities of correction.
Materials and Methods: The study group (n=111) included school-aged children (10-14 years old). The general group of inflammatory diseases of the
respiratory tract (J000-J06) was considered, with a diagnosis of acute respiratory infection (ARI) of viral and bacterial origin and included local inflammationof
the upper respiratory tract with presentation of acute pharyngitis (68.0%), acute bronchitis (22,0%), acute tonsillitis (10,0%).
Results: Dynamic observation of groups of children who received optimized (group 1, n=60) and basic (group 2, n=51) treatment was carried out. The level
of the erythrocyte pool correlated with IL-1 (r=-0,29, p=0,03), IL-4 (r=0,32, p=0,01), TNF-α (r=-0,35 , p=0,006). Creatinine value correlated with IL-10
(r=0,3, p=0,005), γ-IFN (r=0,42, p=0,001), TNF-α (r=0,25, p=0,05). Correlations of ferritin presented positive correlation values with the level of total protein
(r=0,26, p=0,04) and TNF-α (r=0,41, p=0,001).
Conclusions: After the optimized treatment, there was a significant decrease in the reliable levels of CRP and γ-IFN by 7 and 4,4 times (by groups) and 5,8 and
3,2 times (by groups), respectively. Correlation relationships of urea levels with IL-2,4 were detected. The level of the erythrocyte pool correlated with IL-1,4,
TNF-α, Ferritin presented positive correlation values with the level of total protein,TNF-α .
popup.nrat_date
2026-06-13
