Registration Number
2124U012908, Article
popup.category
Текст
Title
Dynamic indicators of the antioxidant system in children with acute respiratory pathology depending on the therapy scheme (AI translated)
popup.author
Horlenko Olesya M.
Pikina Iryna Yu.
Prylypko Lyubomyra B.
Kossey Gabriella B.
Pushkarenko Olga A.
Boisak Iryna M.
Pushkash Ivan I.
Пушкаш Іван Іванович
Горленко Олеся Михайлівна
Пікіна Ірина Юріївна
Прилипко Любомира Богданівна
Коссей Габріелла Барнабашівна
Пушкаренко Ольга Анатоліївна
Бойсак Ірина Михайлівна
Horlenko Olesya M.
Pikina Iryna Yu.
Prylypko Lyubomyra B.
Kossey Gabriella B.
Pushkarenko Olga A.
Boisak Iryna M.
Pushkash Ivan I.
Pushkash Ivan Ivanovych
Horlenko Olesya Mykhailivna
Pikina Iryna Yuriivna
Prylypko Liubomyra Bohdanivna
Kossei Habriella Barnabashivna
Pushkarenko Olha Anatoliivna
Boisak Iryna Mykhailivna
popup.publication
01-01-2024
popup.source_user
Ужгородський національний університет
popup.source
https://dspace.uzhnu.edu.ua/jspui/handle/lib/68143
popup.publisher
Description
Aim: To improve the early diagnosis, course, prediction of the development of Acute Respiratory pathology in children, taking into account the state of antioxidant
system (AOS).
Materials and Methods: The research group included school-age children (10-14 years old) with Acute Respiratory pathologe (n=111) and a control group
(n=25).diseases in comparation.
Results: The highest positive correlation between ferritin and TNF- α (r=0,41, p=0,001); Cortisol with Glutathione peroxidase (r=0,35, p=0,006) were
observed. Ascorbic acid presented positive interactions on the values of Il-6 and Il-2 (r=0,27, 0,26, respectively). The value of vitamin D is represented in
positive interactions with γ-IFN (r=0,30), leptin (r=0,38) and Cu (r=0,32). The negative relationship of Zn with Il-6 was transformed for supporting immune
barriers and protein metabolism.
Conclusions: The level of Glutathione peroxidase increased in 1,6 times, on the other hand, when the basic therapy was prescribed - in 1,1 times (р3<0,01;
р4<0,01; р5<0,01), cortisol level had a reliable tendency to decrease in 1,6. The values of Ascorbic acid increased by almost in 2 times in first group andin 1,4
times in the second group ( p3<0,01; p4<0,01; p5<0,01). After the treatment, the level of vitamin D was identified within the physiological range in the first
group. There are also positive effects of optimized therapy on the state of Copper (p3<0,01), Zinc (p3<0,01), Iron (p3=0,04) trace elements in comparison with
the data of the second group.
popup.nrat_date
2026-06-13
