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Information × Registration Number 0203U006652, 0198U003217 , R & D reports Title The study of the mechanisms of destruction of membrane-associeted structures of immunecompetent cells at immune-inflammations diseases and extreme condition at the patients from ecologically adverse regions for optimization the individual immunecorrection (clinical and experimental researches). popup.stage_title Head Bagdasarova Ingretta, Registration Date 27-06-2003 Organization International Center Astronomical, Medical and Ecological Research popup.description2 During the experiment (used mice CBA and C57BL) with intraperitoneal injection of Staphylococcus aureus the EHF didn't influence on expression of membrane markers of lymphocytes, however impotent change the character expression of peritoneal macrophages and increased the activation of intracellular enzymes, but the combination of EHF and interferon intensified expression of receptors of CD6, CD7, CD16 and IgA, IgG, IgM, IgD on the lymphocytes, increased phagocytosis and the activation of enzymes. Complex of EHF - interferon therapy (with Laferon) of chronic inflammatory respiratory diseases in the children and in women - highlanders with gynecological diseases normalized expression of differentiated and functional CD-markers of immune competent cells, ratio CD4/CD8, increased expression of CD8, decreased immune adhesion of thrombocytes and levels of circulating cytokines - interferon alpha, beta, gamma and tumor narcotizing factor alpha, beta - strengthened activation of L-argenin metabolism especiallyits oxidative NO-synthase way, functional parameters increased-markers of metochondrial, lisosomal and mitotic activity. We first demonstrated a high effectiveness of complex use of EHF and Laferon as an immunecorrective therapy in ecological regions and highlands.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close