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Information × Registration Number 0204U000774, 0101U001326 , R & D reports Title Investigation of regulation of osteogenesis in the teeth and bones with the help of fitoestrogenes for increase the officiency prophylaxic stomatological diseases popup.stage_title Head Levitskiy Anatoliy Pavlovich, Registration Date 23-02-2004 Organization Institute of Stomatology popup.description2 Object of research isoflavones from soy. Purpose - development of preparations with the contents soya isoflavones and technologies of their reception, study toxicological of properties, treatment and preventive efficiency in experiment and clinic. Methods research - technological, analytical, biochemical, toxicological , radioisotope, morphological, statistical. Theoretical and practical results, the novelty - is confirmed osteothropic action and is established expressed caries preventive and paradont-protective effect isoflavones , dedicated from soy. For the first time is established: 1. Ostethropics the action soya isoflavones considerably exceeds them estrogen activity; 2. Soya isoflavones render stimulating action on osteoblastic; 3. Mechanisms of action isoflavones by stimulation of action osteoblastes and synthesis collagen; 4. Glycoside the form isoflavones has more expressed biological action to hydrolyzed. Are developed compoundingand technology of reception of preparations with regulated bythe contents soya isoflavones: tablets EKSO and tooth elixir "Eksodent". Which have expressed cariespreventive, paradont-protective and anti inflammatory of property. The sanction to their introduction is received, the specifications are developed, the patent for the invention is received. The industrial release is adjusted. On how to use of preparations for preventive maintenance and treatment dental of diseases, osteoporosis, crises, different not infectious chronic diseases are submitted. The technology and laboratory rules is developed On reception of substation with the high contents isoflavones. Application- medicine. Product Description popup.authors popup.nrat_date 2020-04-02 Close