Registration Number
0206U000411,
0103U000427
, R & D reports
Title
Multi-component selective synthesis of new sulphur-containing hydrogenated pyridines and condensed analogs, their structure & biological activity
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Head
Krivokolysko Sergey Gennadievich,
Registration Date
25-01-2006
Organization
EAST-UKRAINIAN VOLODIMIR DAL NATIONAL UNIVERSITY
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The principles of general methodology for the directed synthesis of difficult accessible, sulphur-containing hydrogenated pyridines and its ring fused analogs, are developed.This methodology based on the multi-component condensation of aldehydes (ketones) with alpha-substituted thioacetamides and variety of mono- and 1,3-dicarbonyl compounds, methylene active nitriles etc. The structures of the obtained compounds are determined, general principles of reactions courses, as well as optimum conditions for the synthesis of mentioned compounds, were found.
Product Description
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2020-04-02