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0210U003768,
0107U002591
,
To accomplish screening and to study pharmacological activity of modified isoflavonoids and coumarins that can be used as a potential medicine in geriatrics.
Bezverkha Inna St.,
04-03-2010
State Institution "Institute of Gerontology AMS Ukraine"
The research was accomplished to find pharmacologically active substances among modified isoflavonoids and coumarins. The estimated impact on neurological status of animals, blood coagulation system, the functional activity of Liver (cholagogic, cholespasmolitic, and hypocholesterinemic activities) together with antioxidant properties of the Сompounds revealed that most promising compounds for further study are Co1, Co2, Co4, Co7, Co12, and Co27 (as рotential neurotropic (tranquilizing and anxiolytic) agents, as well as 1/08, 3/08, 7/08, 8/08, 16/08, 17/08 and 20/08, which may serve as antioxidant tools. These substances are notable for distinct pharmacological activity and can be used to develop new neurotropic and antioxidant drugs for the needs of practical medicine.
Безверха Інна Степанівна
Заїка Марія Улянівна
Пантелеймонова Тетяна Миколаївна
Шарабура Людмила Борисівна
2020-04-02
Updated: 2025-12-07
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