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Information × Registration Number 0214U001957, 0113U001636 , R & D reports Title Epigenetic results of the irradiation effect on the metabolism of muscles end connective tissue in the age aspect popup.stage_title Head Mardashko Alexsey Alexseevich, Registration Date 02-12-2014 Organization Odesa National Medical University popup.description2 Discovered specialities of interaction terminal plot of glycolysis, ending stage of CAC and gluconeogenesis in myocardium and skeletal muscles of experimental animals. The skeletal muscles are distinction of hight activity of glycolytical processes. Distinction from skeletal muscles, activity enzymes of CAC, in particular, NAD-MDH, is higher in mitochondria of myocardium, more higher containing of CAC metabolites - malate and oxaloacetate, also activity of NAD-MDH, which is binding role between glycolysis and CAC. PEPCC, is catalasing metabolism of cytoplasmatic oxaloacetate in phosphoenolpyruvate, is more active in skeletal muscles, where enzymes activity of CAC is lower, but glycolysis enzymes higher, than in myocardium, from all of this we can suggest, that elementary stage of gluconeogenesis, which includes NADP-MDH, cytoplasmatic NAD-MDH and PEPCC, more active came in tissue with high activity of glycolysis. The glycolytical oxidoreduction stage of it higher in skeletal muscles than in myocardium, but myocardium has high shunt activity of cytoplasmatic MDH, which involves cytoplasmatic NADH+H+ in tissue respiratory system. Product Description popup.authors Будаленко Ольга Іванівна Васильєва Антоніна Георгіївна Дімова Алла Анатоліївна Костіна Аліна Анатоліївна Кузьміна Ала Володимирівна Мардашко Оксана Олексіївна Мардашко Олексій Олексійович Степанов Геннадій Федорович Сторчило Ольга Вячеславівна Терещенко Людмила Олександрівна Щербаков Сергій Васильович popup.nrat_date 2020-04-02 Close