Registration Number
0214U002006,
0112U002407
, R & D reports
Title
The study of the N-stearoiletanolamine radiomodifying properties in the experiments on the rats
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Head
Derevyanko Ludmyla Petrivna; Tal'ko Viktoriya Vasylivna,
Registration Date
13-01-2014
Organization
State institution "National research centеr for radiation medicine of the National academy of medical sciences of Ukraine "
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Object: prooxidant and antioxidant systems, functional status gonadal axis,concentration of testosterone, nitrite-anion, hematological parameters of peripheral blood of mature male rats (120). Objective: To verify the changes pro-, antioxidant systems and the functional state of gonadal axis in irradiated male rats in different conditions of N-stearoylethanolamine and emotional-painful stress application. Methods: biochemical, enzyme immunoassay, hematological and statistical. It is established that under the combined influence of gamma-irradiation males rats in dose 6,0 Gy and emotional-painful stress and N-stearoylethanolamine injection at a dose of 10 mg/kg (before and after irradiation) were observed different direction changes of indices (concentration of TBA-active products, the activity of catalase, the concentration of testosterone and nitrite-anion, hematological indices of peripheral blood). These changes indicate the radiomodified action of preparate.
Product Description
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Атаманюк Н.П.
Дерев'янко Л.П.
Родіонова Н.К.
Талько В.В.
Фролова Н.О.
Шелковський М.В.
Яніна А.М.
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2020-04-02
