Search academic texts

Information × Registration Number 0217U000009, 0116U000184 , R & D reports Title To develop a treatment schemes of patients with respiratory sarcoidosis with resistance of corticosteroids to therapy or contraindications to their prescribe popup.stage_title Head Gavrysiuk Volodymyr, Registration Date 05-01-2017 Organization Institute of tuberculosis and pulmonology named by F. G. Yanovsky popup.description2 Object - 33 patients with respiratory sarcoidosis with resistance of corticosteroids to therapy or contraindications to their prescribe. Aim - increase the effectiveness of treatment in patients with respiratory sarcoidosis with resistance of corticosteroids to therapy or contraindications to their prescribe through the development of optimal schemes for the use of second-line drugs. Methods - clinical, chest computed tomography, spirometry. It is established that the use of methotrexate 10 mg 1 time per week in patients with contraindications to corticosteroids therapy, 6 months can achieve of clinical cure or regression process in 84,2 % of patients. In patients with sarcoidosis, resistance of corticosteroids to therapy, methotrexate monotherapy in most cases (71,0 %) is ineffective. Sphere of application - pulmonology, phthisiology Product Description popup.authors Беренда Олена Анатоліївна Гаврисюк Володимир Костянтинович Гуменюк Галина Львівна Дзюблик Ярослав Олександрович Заворотня Неоніла Павлівна Лещенко Сергій Іванович Меренкова Євгенія Олександрівна Морська Наталія Дмитрівна Намазова Юлія Вікторівна Ячник Анатолій Іванович popup.nrat_date 2020-04-02 Close