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Information × Registration Number 0217U001588, 0112U000254 , R & D reports Title Target-oriented search for the novel antimicrobial, antiviral and antitumor agents popup.stage_title Head Dubey Igor, Доктор хімічних наук Registration Date 02-03-2017 Organization Institute of Molecular Biology and Genetics of NASU popup.description2 New approaches to the development of bioactive compounds based on the use of specific biological targets and computer modeling were proposed. New structures and methods of synthesis of numerous new compounds of various classes were developed. They were tested in vitro in enzymatic systems and in cell cultures. Efficient inhibitors were found to be active at low micro- and submicromolar concentrations. New mechanisms of antiviral action of 2'-5'-oligoademylates based on their interaction with proteins of blood were investigated. Positive effect of isatison and nanosilver on plant productivity was established. Product Description popup.authors Ільченко М.М. Бджола В.Г. Волинець Г.П. Гудзера О.Й. Заїка Л.А. Кацан В.А. Коваленко О.П. Корнелюк О.І. Костіна В.Г. Костенко О.М. Криворотенко Д.В. Левченко С.М. Лукашов С.С. Микуляк В.В. Негруцька В.В. Потопальський А.І. Ткачук З.Ю. Тукало М.А. Яремчук Г.Д. Ярмолюк С.М. popup.nrat_date 2020-04-02 Close