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Information × Registration Number 0217U006068, 0116U004138 , R & D reports Title Creating of a new promising bioactive compounds based on sulfuro- and nitrogen-containing derivatives of carbocyclic and heterocyclic structures popup.stage_title Head Novikov V., Registration Date 03-02-2017 Organization Lviv Polytechnic National University popup.description2 The method of amino and diamino-9,10-anthracenediones N-acylation in the system of strong carboxylic acid-ammonium thiocyanate was proposed. It was obtained a number of N-benzoyl-N'-thioureas-9,10-anthracenediones, based on which there were developed approaches to the synthesis of new N-(9,10-dioxo-9,10-dihydroanthracene-1-yl)-2-(N-benzoylimino)thiazoles, [(5-phenyl-4H-1,2,4-triazole-3-yl)amino]-anthracene-9,10-diones and [(1-benzoyl-1H-tetrazol-5-yl)amino] anthracene-9,10-diones, 1,2,3-substituted guanidines. New amino acid derivatives of 2-chloro-N-(9,10-dioxo-9,10-dihydroanthracene-1-yl)acetamide were synthesized and the thiocyanation features of 2-chloro-N-(9,10-dioxo-9,10-dihydroanthracene-1 (2)-yl)acetamides and products of their transformation were investigated. Experimental biological screening has revealed substances with high bactericidal, fungicidal, antioxidant, tyrosine kinases activity. Product Description popup.authors Василюк С.В. Зварич В.І. Лубенець В.І. Монька Н.Я. Мусянович Р.Я. Нагурська А.М. Наконечна А. В. Новіков Володимир Павлович Прохера О.В Стасевич М.В. Хом'як С.В. Шиян Г.Б. popup.nrat_date 2020-04-02 Close