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Information × Registration Number 0219U000196, 0117U004430 , R & D reports Title To investigate antitumor properties of membrane channel bloker verapamil in the glioma tumor clinic that was detected in the experiment and estimate its possibilities for this destination. popup.stage_title Head Gridina Nina Yakivna, Registration Date 18-01-2019 Organization Academician A.Romodanov Institute of neurosurgery AMSc of Ukraine popup.description2 The aim of the work was to increase the effectiveness of treatment of patients with glial tumors as a result of the use of small doses of verapamil hydrochloride in order to prevent the onset of recurrence of gliomas in the remote postoperative period. The conducted search robot confirmed the results obtained in the experiment on rats with graft glioma 101.8 (analogue of human glioblastoma) anti-tumor properties of the pharmacological drug verapamil hydrochloride, which was used in small doses (10,000 times dilution of the drug) in patients with glioblastoma in the postoperative period after chemotherapy courses until the end of the patient's life.The use of verapamil contributed to the inhibition of glioblast recurrence and prolonged life of patients in the remote postoperative period on average by 8 months compared to those who did not take the drug. At the end of the topic, all patients lived throughout the year, and some patients lived more than 1.5-2 years. Product Description popup.authors Величко О. М. Веселова О.І. Главацький О.Я. Гридіна Н.Я. Драгунцова Н.Г. Морозов А.М. Нахаба О.О. Розуменко А. В. Розуменко В.Д. popup.nrat_date 2020-04-02 Close