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Information × Registration Number 0219U100021, 0117U001929 , R & D reports Title Making of new dermal wound coverings for treatment of massive burns and traumatic skin lesions with other genesis popup.stage_title Head Lukash Lyubov L., Доктор біологічних наук Registration Date 04-01-2019 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description2  In the second stage within the preclinical trials on skin burn models at rats the efficiency and safety of biotechnological wound coverings on the basis of a carbopol hydrogel with inclusion of stem cells of line 4BL or acellular conditioned medium (ACM) was established. Level of regulatory proteins (MMP-2 and HIF-1alpha) in blood of animals in the experimental group significantly decreased that can indicate earlier completion of degradation processes of an extracellular matrix and earlier completion of stem cells differentiation during wounds healing. The acute or subchronic toxicity after external application of medicinal preparations was absent. Product Description popup.authors popup.nrat_date 2020-04-02 Close