Registration Number
0221U106748,
0118U002054
, R & D reports
Title
The scientific basis of creating functionalized polymers and nanocomposites baseg on natural compounds
popup.stage_title
Head
Riabov Sergiy V., Доктор хімічних наук
Registration Date
19-12-2021
Organization
Institute of Chemistry of Macromolecular Compounds of the National Academy of Sciences of Ukraine
popup.description2
The functional derivatives of starches (phosphates) were synthesized, conducted studies of their physical and chemical properties and tested as carriers of medicinal products in the work. Features of the structural organization and thermomechanical properties of stoichiometric PEC based on functionalized samples of cyclodextrin and chitosan, as well as metal-containing nanocomposites with nanoparticles (Ag) and Cu2O formed by chemical and thermochemical methods of recovery of cations (Ag +) and (Cu2+) are investigated. It has been established that the degree of swelling of the received matrices is higher with a low content of phosphate groups in starch. The use of the starch derivative matrix (FS) slows the rate of release of clotrimazole (more than 2 times), presumably, due to the formation of hydrogen. It is established that the studied copper and silver-containing nanocomposites based on stoichiometric PECs have high antibacterial activity relative to gram-positive (S. aureus) and gram-negative (E. coli) test cultures.
Product Description
popup.authors
Demchenko Valeriy L.
Kobylinskiy Sergiy M
Kobrina Larysa V.
Sinelnikov Sergiy I.
Shtompel Volodymyr I.
popup.nrat_date
2021-12-19
