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Information × Registration Number 0221U107053, 0120U100930 , R & D reports Title Development of bioconjugates of environmentally friendly Ag2S quantum dots as new tools for intracellular imaging popup.stage_title Head Borova Mariya M., Кандидат біологічних наук Registration Date 26-12-2021 Organization Institute of Food Biotechnology and Genomics of the National Academy of Sciences of Ukraine popup.description2  A protocol for obtaining luminescent bioconjugates of Ag2S nanoparticles with antibodies was developed in this work,. Their physicochemical characteristics have been studied and the possibility of their use in fluorescence microscopy has been shown. Bioconjugation of quantum dots with antibodies is the most studied today, as such conjugates of molecules with luminescent nanoparticles are the basis for the creation of biosensors, as well as the novei systems for diagnosis and delivery of drugs based on nanomaterials. The presented development has certain advantages, in particular, the use of the obtained bioconjugates with antibodies does not require expensive secondary antibodies, which are attached to the luminescent label in standard methods of immunocytochemistry. In addition, synthesized quantum dots are characterized by long-term photostability and increased brightness in contrast to common organic dyes. Product Description popup.authors Borova Mariya M. Horiunova Inna I. Kapush Olha A. Plokhovska Svitlana H. Pushkareva Nadiia О. popup.nrat_date 2022-03-09 Close