Registration Number
0222U000651,
0120U103099
, R & D reports
Title
Translation elongation factor eEF1A as a new antigen in the formation of autoimmune antibodies in type 1 diabetes and other autoimmune diseases.
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Head
Negrutskyii Borys S., Доктор біологічних наук
Registration Date
14-01-2022
Organization
Institute of Molecular Biology and Genetics of NAS of Ukraine
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The object of study – the autoantibodies to elongation translation factors. The aim of the work is - to study the presence of autoantibodies to eEF1A in the serum of patients with DMT1 from the Slavic population. Research methods - enzyme-linked immunosorbent assay, statistical methods. The presence of autoantibodies to eEF1A translation elongation factor in these samples was studied using serum samples from patients with type 1 diabetes of Ukrainian and Polish population. The presence of a certain amount of autoantibodies to eEF1A in blood samples of patients with type 1 diabetes of Ukrainian and Polish origin is shown. This indicates the possible universal nature of the presentation of eEF1A as an autoantigen in type 1 diabetes in the Slavic and South Asian populations.
Product Description
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Bondarchuk Tetyana V.
Lysetskyi Igor L.
Luk`yanenko Ganna I
Novosylna Oleksandra V.
Porubleva Larysa V.
Shalak Viacheslav F.
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2022-03-09
