Registration Number
0222U002711,
0116U006963
, R & D reports
Title
Research and simulation of molecular dynamics biomarker volatile compounds in the elimination of gas transport currents in biological structures.
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Head
Musyra Anatoliy G., Доктор біологічних наук
Registration Date
15-02-2022
Organization
Institute Of Applied Problems Of Physics And Biology Of The National Academy Of Sciences Of Ukraine
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The study of the characteristics of gas-sensitive materials to acetone and ammonia in ultra-low concentrations has been developed and carried out. The role of certain dyes, quantum dots, natural coumarins and other substances immobilized in polymer matrices in increasing the fluorescent signal and sensitivity to ultralow concentrations of certain biomarkers is shown. The efficiency of application of ionic mobility technology for detection of a group of compounds of ultralow concentration in exhalation at atmospheric pressure is shown. A sample of the device has been developed. An analytical description of the processes of movement and spatial distribution of ultra-low-concentration compounds in the alveolar-bronchial tract during respiration has been created. compounds in the lungs during cyclic respiration and complications of uneven ventilation of bronchopulmonary structures, alveoli and alveolar-capillary structures and capillary hemodynamics. Simulation models have been created and their software testing has been carried out. Gas-sensing materials fluorescently sensitive to acetone and ammonia were synthesized. Layout samples of non-invasive pulse oximetry, carboxymetry, CO-metry devices were created.
Product Description
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Krivets Serhij V
Mamilov Serhii O.
Sokolov Volodumir O
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2022-03-09
