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Information × Registration Number 0223U000729, 0121U112939 , R & D reports Title Fulfillment of the tasks of the perspective plan of development of the scientific direction "Biology and health care" popup.stage_title Head Ostapchenko Liudmyla І., Доктор біологічних наук Registration Date 19-01-2023 Organization Taras Shevchenko National University of Kyiv popup.description2 In part 1 "Investigation of the molecular and biochemical mechanisms of the functioning of metabolic and signaling pathways in conditions of normal and pathologically altered metabolism" the effect of low molecular fragments of collagen and melatonin in conditions of normal and pathologically altered metabolism was studied. In part 2 "Study of histomorphological processes in tumor models and in precancerous conditions, and in their correction with biologically active drugs" the histomorphological processes in tumor models and in precancerous conditions and in their correction of the newly formed C60-PL nanocomplex were studied. In part 3 "Investigation of the species-, variety- and tissue-specificity of the accumulation of secondary metabolites of plants, algae and fungi (polyphenols, terpenoids, hydroxycinnamic acids, naphthodianthrones, iridoid glycosides), which are promising in the fight against the consequences of COVID-19 and related diseases of the respiratory and circulatory systems and gastrointestinal tract" selected substances that are promising in the fight against the consequences of COVID-19 and related diseases of the respiratory, circulatory systems and gastrointestinal tract. The obtained results of the study of the composition of secondary metabolites of the studied collection of medicinal plants and its effect on the metabolic profile of mouse macrophages. In part 4 "Development of a complex psychological, psychiatric and neurophysiological model for overcoming the negative consequences of the impact of the COVID-19 pandemic", the impact of the COVID-19 pandemic on the quality of psychiatric care was studied. In part 5, "Development and optimization of obtaining collagen from various sources, its modification and research of potential impact on metabolic processes in the body. Product Description popup.authors Gorobeiko Maksym B. Dziubenko Natalia V. Kalmykova Olesia O. Kravchenko Olga О. Mishchenko Lidiya Trochimivna Nuzhyna Nataliya V. Nuryshchenko Nataliia Ye. Skivka Larysa M. Falalieieva Tetiana M. Chumak Stanislav A. Shevchyk Vasyl L. popup.nrat_date 2023-01-19 Close