Registration Number
0223U001046,
0122U200335
, R & D reports
Title
Exploratory study of health related physiological and biochemical parameters to identify simple, robust and relevant biomarkers
for therapeutic interventions for PTSD patients
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Head
Serhiienko Viktoriia O., Доктор медичних наук
Registration Date
24-01-2023
Organization
Danylo Halytsky Lviv National Medical University
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The purpose of the work is to determine the physiological, biochemical, endocrine and immunological changes in servicemen with PTSD compared to healthy individuals with the aim of selecting some of them as biomarkers for future studies of the effectiveness of new treatment methods; to assess the degree of these changes in order to rationally choose the optimal interventions that would correct the detected changes.
In the course of work, a number of diagnostic examinations were conducted for patients from the Military Medical Clinical Center of the Western Region (Military Medical Clinical Center of the Western Region) - military personnel hospitalized for treatment and/or rehabilitation. Questionnaires were filled out, most of which were used to determine the presence or absence of PTSD symptoms, namely: PTSD Initial Screening Questionnaire; Mississippi scale for assessment of post-traumatic reactions (military version); scale for assessing the impact of a traumatic event (Impact of Event Scale - Revised (IES-R)); questionnaire for the definition of a generalized anxiety disorder (GAD-7); patient health questionnaire (PHQ-9); Wayne Questionnaire. A study was conducted from the endocrinological/metabolic block: investigating the potential impact of PTSD on low-grade inflammation, oxidant stress, and impairment of carbohydrate metabolism and establishing correlations between these parameters.
Product Description
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Holota Serhii Mykoloiovych
Derkach Zenoviy Volodymyrovych
Kozjol Lilia I
Melnyk Stanislav V
Pylypchuk Sophia I
Yatskevych Ostap Yaropolkovych
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2023-01-24
