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Information × Registration Number 0223U005721, 0123U100229 , R & D reports Title Development of quality control methodology and standardization of the antiviral drug favipiravir popup.stage_title Head Yehorova Alla V., Доктор хімічних наук Registration Date 29-12-2023 Organization Physico-Chemical Institute O. Bogatsky National Academy of Sciences of Ukraine popup.description2  The object of study - AFI FAVIPIRAVIR (antiviral drug). The subject of the study is the structure, physical and chemical characteristics, quality control methods of API FAVIPIRAVIR (determination of related substances, assay). Research methods – molecular absorption spectroscopy (UV and visible), HPLC, Raman scattering spectrometry, infrared spectroscopy, differential scanning calorimetry, laser diffractometry, chromatography-mass spectrometry. The main idea of the work was the experimental solving of the scientific problem, which is manifested in the development, optimization and validation of quality control methods of AFI FAVIPIRAVIR in accordance with the requirements of the SPU, establishing the physicochemical properties of the AFI and the ionization constant which necessary for the pharmaceutical dossier and industrial production. Product Description popup.authors Yehorova Alla V. Aleksandrova Daria I. Scrypynets Yuliia V. Chebotarska Inna I. popup.nrat_date 2023-12-29 Close