Registration Number
0226U002766,
(0123U101168)
, R & D reports
Title
New principles of synthesis of fluorescent materials and biologically active N,S-containing heterocycles.
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Створення нових флуорофорних матеріалів на основі ксантенових барвників.
Head
Farat Oleh K., Доктор хімічних наук
Registration Date
05-03-2026
Organization
Ukrainian State University of Science and Technologies
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Creation of new heterocyclic compounds with predicted optical and pharmacological properties. Establishing the limit parameters of the new reactions application to simplify the synthesis of new compounds and materials.
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The object of research is NIR (Near InfraRed) fluorescent dyes, photocells for solar cells and optical filters, as well as N,S-alpha-amidoalkylation and related processes for the creation of functionalized heterocyclic systems - potential pharmaceutical substances. The purpose of the work is to determine the optimal conditions for the synthesis of a number of xanthene dyes and to study their spectral properties; development of convenient methods for obtaining new types of N,S-amidoalkylating and related reagents with heterocumulene groups. Research methods are chemical synthesis, thin-layer chromatography (TLC), X-ray diffraction analysis (XRA), infrared spectroscopy (IR) and nuclear magnetic resonance (NMR) spectroscopy, ultraviolet spectroscopy (UV), mass spectrometry and quantum chemical calculations. It is developed a Method for synthesizing xanthene dye with volumetric heterotransition; Method for synthesizing thiosemicarbazide derivatives with an alkylamide fragment; Method for selective synthesis of fused pyridines. The field of use of work results: C 21.10 production of basic pharmaceutical products, C 20.12 Production of dyes.
Product Description
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Pavlo V. Zadorozhnyi
Svеtlana А. Varenіchenko
Oleh K. Farat
Anton V. Kovtun
Mykola V. Smetanin
Rostyslav Р. Svoiakov
Valeriia V. Pavlova
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2026-03-05
