Registration Number
0209U010576,
0107U004912
, R & D reports
Title
The cytokine of X and XII/XII families influence on regenerative function of heart and liver in experimental conditions
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Head
Kholodkova Olena Leonidivna,
Registration Date
16-12-2009
Organization
Odessa state medical university
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Research results of the structural and functional peculiarities of myocardium and liver against a background of induced cardiomyopathy, liver fibrosis, toxic hepatitis and after the correction of these pathological states by means of EPO and G-CSF are submitted. Protein profile features in blood serum and the wall of the left ventricle were revealed. It was shown that EPO and G-CSF make a positive influence on the restoration of the myocardium under the toxic effects of adriblastin. It was also shown that EPO introduction leads to involution of pathological processes at any stage of liver fibrosis. G-CSF usage leads to reliable decrease of specific density of the stromal components, apoptotic hepatocytes with karyopyknosis, karyorecsis, karyolysis at any stage of fibrosis formation.
Product Description
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Вернідуб Ірина Вікторівна
Гудіна Ірина Вікторівна
Десятський Валерій Володимирович
Кошельник Олена Леніанівна
Нескоромна Наталія Олександрівна
Ославська Тетяна Михайлівна
Пихтєєв Дмитро Михайлович
Попов Олександр Георгійович
Слученко Олександр Миколайович
Холодкова Олена Леонідівна
Щербатюк Аліна Леонідівна
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2020-04-02
