Registration Number
0213U003083,
0110U002198
, R & D reports
Title
Research of regenerative potential of stem cells of different type at damage of nervous and immune systems
popup.stage_title
Head
Butenko Gennadij Michailovich,
Registration Date
18-01-2013
Organization
Institute of genetic and regenerative medicine Acad.Med.Sci. of Ukraine
popup.description2
Model experiences organotipichnoy ischemic hippocampus in vitro culture by CGD. Stem cells (NSCs and ITC) after transplant hippocampus slices organotipichnoy culture survived and changed their morphology, indicating their differentiation state. MSK_PNG from the hair follicle vibris mice are capable of clonal growth, self-renewal and directed differentiation. The possibility of culturing MSCs-associated gas in the three-dimensional structures based on collagen and fibrin gel. In the bone marrow of animals timektomirovanyh COC-F decreases, which coincides with the decline of CD4 + cells and thymic hormone deficiency. Synthetic thymic hormone affects in vitro the ability of colony formation of stromal progenitor cells of the bone marrow timektomirovannyh animals. After thymectomy imbalance in the directed differentiation of bone marrow ITC osteogenic and adipogenic direction. Inhibitory effect on bone marrow ITC mitogen-induced proliferation of splenocytes in vitro is more pronounced in cells from timektomirovannyh animals. The features of the proliferation of cultures of visceral and subcutaneous adipose tissue, and bone marrow cells of mice. The possibility of a phased osteogenic differentiation ITC PZHT with previous chondrogenic induction. The efficiency of the cultivation and osteogenic differentiation in the direction of ITC fat culture microarray method. Technologies of preparation of hydrogels based karbomna and agarose according to their physico-chemical properties of the cells for further settlement.
Product Description
popup.authors
Васильєв Р.Г.
Кирик В.М.
Лабунець І.Ф.
Півнева Т.А.
Родніченко А.Є.
Скибо Г.Г.
Цупиков О.М.
popup.nrat_date
2020-04-02