Registration Number
0214U008315,
0114U006008
, R & D reports
Title
The development of new antiepileptic compounds to inhibit hippocampal seizures
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Head
Isaeva Olena Valentynivna,
Registration Date
25-12-2014
Organization
Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine
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During the first stage of the projest, it was found that thrombin increases excitability of neurons in the immature rat hippocampus NMDA-independent manner. It has been shown that thrombin controlled constant potential increases sodium current and affect the resting membrane potential, thus increasing the likelihood of seizures in epileptic brain injury. This research will help develop a new strategy of medical intervention in order to prevent the occurrence of epilepsy due to brain injury.
Product Description
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Ісаєв Дмитро Сергійович
Ісаєва О.В.
Венгренюк Артем Васильович
Запухляк О.С.
Максимюк Олександр Петрович
Нецик О.В.
Романов Артур Костянтинович
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2020-04-02
