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Registration Number

0215U003051, R & D reports

Title

Comparative analysis of algorithms of topometric preparation and planning of conventional and conformal radiation therapy on linear accelerators.

Head

Starenkyi V.P.,

Registration Date

16-01-2015

Organization

Grigor'ev Institut for Medical Radiology

Description

Research object. Technologies of planning of radiotherapy of head and neck and thoracic tumors, methods of optimization and verification of irradiation schemes. Research objective. To unify the schemes of topometric arrangement and planning of conventional and conformal radiotherapy on linear accelerator for treatment of head and neck and thoracic tumors. Research methods and equipment. X-ray, morphological, clinical instrumental, statistical, universal dosimeter UNIDOS, linear accelerator Clinac 600C. Theoretical and practical results. International and national scientific methodological sources concerning elaboration and application of method of topometric preparation and planning of irradiation of head and neck and thoracic tumors by photons from linear accelerators were analyzed. The structure and technical supply of leading radiology departments in Ukraine were examined and their needs regarding the organizational and technical modernization and implementation of optimized protocols of planning of radiotherapy by photon linear accelerators were defined. Methods of pre-irradiation preparation of patients with lung and prostate cancer were elaborated. Novelty. For the first time the necessity of a state program of gradual multipart modernization of radiotherapy centers in Ukraine was substantiated, that included a formation of leading inter-regional centres of competence and peripheral centers for public service. Considering the established conditions of technical supply and methodological approaches to the topometric preparation, immobilization and planning of radiotherapy in leading cancer centers across the world, the most rational methods of pre-radiation preparation for head and neck and thoracic tumors were defined for Ukraine. New methods of pre-radiation preparation of patients with lung or prostate cancer were suggested. Implementation effectiveness. Elaborated methods of pre-radiation preparation of patients with lung or prostate cancer allows to increase the accuracy of irradiation volume estimates and to decrease the damage of surrounding normal tissues. Area of application - radiation therapy, oncology.

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