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Information × Registration Number 0215U008103, 0112U006943 , R & D reports Title Allelic polymorphism of genes involved in monogenic and complex disorders development popup.stage_title Head Livshits Ludmila Avramovna, Registration Date 08-12-2015 Organization Institute of Molecular Biology and Genetics popup.description2 The collection of DNA samples of the patients with allelic variants of MTHFR, F5, F2, ESR1, ADRB2, ITGB3 та CYP2C9 genes belonging to the marker panel of genetic predisposition to ischemic stroke and miscarriage at females. Diagnostic methods for these gene allelic variants analyses were designed. It was revealed that some IL10 allels were markers of genetic predisposition to ischemic stroke, and some IL10 genotypes were markers of genetic predisposition to miscarriage. It was shown that some homozygous IL6 и ESR1 gene allels might be genetic markers of successful gestation at first trimester. The methods for CYP21A2gene /CYP21A1P pseudogene and SMNII gene analyses were designed. Product Description popup.authors Грищенко Н.В. Кравченко С.А. Нечипоренко М.В. Пампуха В.М. Соловйов О.О. Татарський П.Ф. Чернушин С.Ю. popup.nrat_date 2020-04-02 Close