Registration Number
0223U000196,
0120U103281
, R & D reports
Title
To improve the methods of cardiac rehabilitation in patients after acute coronary syndrome with ST segment.
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Head
Talaeva Tetiana V., Доктор медичних наук
Fedkiv Svitlana V., Доктор медичних наук
Shumakov Valentyn O., Доктор медичних наук
Registration Date
05-01-2023
Organization
State Institution "National Scientific Center "Institute of Cardiology named after academician M.D. Strazhesko" of the National Academy of Medical Sciences of Ukraine
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39 patients with STEMI who underwent urgent stenting of the infarct-causing artery and 5 patients with unstable angina were included in the study. The number of KPE (phenotype CD45+/CD34+) in peripheral blood was determined by flow cytometry using reagents for the determination of CD34, CD45 differentiation clusters manufactured by BeckmanCoulter Inc. months after a myocardial infarction and restoration of endothelial function in patients with a favorable course, as evidenced by a statistically higher number of KPE after exercise in the group with a favorable course and high tolerance to physical activity. In patients, a decrease in KPE during exercise is associated with a worse disease prognosis. The de Ritis coefficient in combination with the dynamics of KPE growth can be seen as a strong and independent prognostic predictor of tolerance to physical activity levels in patients after acute MI during long-term follow-up.
Product Description
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Babiy Liana M
Voloshyna Oksana V
Pogurelska Olena P
Ponomariova Galina V.
Tereshchenko Nataliia M.
Tretyak Iryna Vasylivna
Shumakov Oleksandr V.
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2023-01-05
