Registration Number
0223U001356,
0119U103958
, R & D reports
Title
To study the peculiarities of the course of multifocal symptomatic epilepsy and to develop differentiated approaches to the surgical treatment
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Head
Tsymbaliuk Vitalii Ivanovych, Доктор медичних наук
Registration Date
28-01-2023
Organization
The State Institution Romodanov Neurosurgery Institute National Academy of Medical Sciences of Ukraine
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Реферат (англійською мовою) 75p., 14 tables., 8 figures., 60 references.
STRUCTURE EPILEPSY, NEUROPSYCHOLOGICAL DISTURBANCES, MULTILOBAR RESECTIONS, CALLOSOTOMY, FUNCTIONAL HEMISHEROTOMY
Object of study: multifocal epilepsy, epileptic seizures
Subject of study: clinical manifestations of epilepsy, cognitive and psychoemotional disorders, differentiated neurosurgical interventions.
Aim of study: to improve the results of surgical treatment of multifocal epilepsy due to a differentiated approach to the choice of surgical intervention depending on the clinical manifestations of the disease and structural and functional changes of the brain.
Factors that determine the severity and prognosis of the course of epilepsy have been established. Unfavourable factors include the early onset of epilepsy, a high frequency of epileptic seizures resistant to antiepileptic therapy, progressive epileptic encephalopathy, and the presence of bilateral epileptic paroxysmal brain activity.
Established neuropsychological criteria for prognosis regarding memory-intellectual decline. Unfavourable factors include the presence of localization of epileptic or epileptic foci in the dominant hemisphere and the duration of the disease.
It has been established that the best results of surgical treatment of multifocal epilepsy occur in case of localization of epileptic foci or diffuse epileptic focus within one hemisphere. In such cases, isolated multilobar resections or in combination with disconnection operations lead to a complete control of epileptic seizures in the vast majority of patients.
It has been established that control of epileptic seizures and improvement of the psycho-emotional sphere after surgical treatment occurs due to the prevention of secondary brain damage, secondary epileptogenesis and the elimination of long-term, continuous interictal paroxysmal activity.
Product Description
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Bunyakin Vyacheslav Mykhailovych
Dychko Serhii Mykolayovych
Kanaykin Oleksiy Mykhailovych
Kostiuk Kostiantyn Romanovych
Kostyuk Mikhalo Romanovych
MEDVEDYEV YURIJ MYKHAYLOVYCH
Popov Andriy Oleksandrovich
Сheburakhin Valerij Valerijovych
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2023-01-28
