Звіт по науково-дослідній роботі. Присяжнюк Анатолій Євтихійович. Дослідження основних чинників формування рівнів захворюваності на злоякісні новоутворення учасників ліквідації наслідків аварії на ЧАЕС 1986–1987 рр., осіб, евакуйованих із зони відчуження, мешканців забруднених радіонуклідами територій за результатами епідеміологічного моніторингу за період 1990–2022 рр.

Registration Number

0224U000809, 0122U001426 , R & D reports

Title

Research of the main factors of formation of levels of malignant neoplasms of participants in the liquidation of the Chernobyl accident of 1986-1987, persons evacuated from the exclusion zone, residents of radionuclide-contaminated areas according to the results of epidemiological monitoring for the period 1990-2022.

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Head

Prysiazhniuk Anatolii Ye., Доктор медичних наук

Registration Date

12-01-2024

Organization

State institution "National Scientific Center of Radiation Medicine of the National Academy of Medical Sciences of Ukraine"

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Subject of the study: clean-up workers participated in clean-up works in 1986-1987 (74128 persons); evacuees (65300 persons); residents of the territories most heavily contaminated with radionuclides of Kyiv and Zhymomyr oblasts (173314 persons). Aim of the study: To define level, structure and dynamics of cancer incidence in affected groups during post-accident period up to 2021 and to estimate an acceptable model of radiation associated cancer risk for Ukrainian population. Research methods: epidemiological, statistical, program and mathematical. All cancers incidence rates exceed the national level only in clean-up workers of 1986-1987. SIR (standardized incidence ratio) = 106.6 % (95 % confidence interval CI: 104.9-108.5). Significant excess of thyroid cancer was observed in clean-up workers - 4.5-fold, evacuees - 3.8-fold, residents of radioactive contaminated territories - 1.3-fold. Leukemia and lympoma incidence rate in clean-up workers and evacuees exceeds the national level in 1.5 times. Breast cancer incidence in clean-up workers is higher in 1.6 times comparing with expected level. In women evacuees and residents of the contamitated territories breast cancer incidence rate increases too. Publications: 2 articles in national journals (1 - in press), 4 abstracts, participating in 5 conferences, information letter - 1. Field of use: bodies and institutions of the Ministry of Healthcare of Ukraine, institutions of the National Academy of Medical Sciences of Ukraine. Key words: CHORNOBYL ACCIDENT, MALIGNANT TUMOURS, LIQUIDATORS, EVACUEES, RESIDENTS OF TERRITORIES MOST CONTAMINATED WITH RADIONUCLIDES

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Babkina Nataliia G.
Bekishev Gennady Yuriyovych
Gudzenko Nataliya A.
Danevych Svitlana A.
Fuzik Mykola Mykolayovych
Khukhrianska Mariya V.
Khukhrianska Olena M.

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2024-01-12