Registration Number
0226U001962,
(0123U101095)
, R & D reports
Title
Explore the action of the mechanisms formation of complications in the acute and intermediate periods of combat craniocerebral trauma and development of the method of comprehensive prevention of them
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Вивчити особливості механізмів формування ускладнень в гострому та проміжному періодах бойової черепно-мозкової травми та розробити методику їх комплексної профілактики
Head
Posokhov Mykola F., Кандидат медичних наук
Registration Date
04-02-2026
Organization
State institution "Institute of Neurology, Psychiatry and Narcology, National Academy of Medical Sciences of Ukraine"
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Explore the pathogenetic mechanisms of the formation of complications of combat craniocerebral trauma in the acute and intermediate periods, to theoretically and clinically substantiate their complex treatment
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Research and Development Report: 312 pages, 40 tables, 1 appendix, 256 references.
Keywords: combat traumatic brain injury, pathogenesis, clinical presentation, diagnosis, complications, treatment and prevention of complications.
Subject of the study – etiopathogenetic mechanisms of complication development in the acute and intermediate periods of combat traumatic brain injury (cTBI) and their prevention.
Relevance. Combat traumatic brain injury is a pressing problem in modern neurosurgery and military medicine. Complications arising in the acute and intermediate periods of traumatic brain disease develop as a result of the combination of primary injury and secondary pathogenetic processes, have a prolonged course, and negatively affect functional status, psychoemotional condition, and social adaptation of affected individuals. This determines the need to improve approaches to their early diagnosis and comprehensive prevention.
Aim of the study – to investigate pathogenetic mechanisms of complication development during different periods of the course of cTBI and to develop a method for their early diagnosis and prevention.
Materials and methods. A total of 165 combatants with closed traumatic brain injury of 2 days to 12 months’ duration were examined. Clinical and neurological, psychological, neuro-ophthalmological, otoneurological, neuroimaging, laboratory, and electrophysiological methods were applied.
Results and conclusions. It was established that cTBI is characterized by more pronounced and prolonged secondary brain damage compared to civilian traumatic brain injury. The structure of complications is dominated by psychoemotional, cognitive, and cerebrospinal fluid dynamic disorders with a tendency toward progression. The proposed method of early diagnosis and comprehensive prevention contributes to a reduction in complication rates and improvement of treatment outcomes.
Product Description
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Shliakhova Anna V.
Olha H. Berchenko
Anna M. Titkova
Valentyna V. Heiko
Olha V. Kyrychenko
Ihor O. Kutovyi
Yevheniia V. Liekomtseva
Zaza M. Lemondzhava
Ihor O. Poliakh
Oleh V. Horbunov
Nataliia V. Stepanenko
Oksana S. Ishchenko
Elina V. Suprun
Nataliia O. Levicheva
Andrii V. Galii
Serhii I. Bibichenko
Mykola O. Drohvalenko
Valentyna O. Prylepa
Sofiia I. Shneiderman
Viktoriia S. Buriak
Dymytro S. Samokhin
Yevheniia Y. Chepa
Roman V. Korniienko
Olha M. Peretiachenko
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2026-02-04
