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Information × Registration Number 0201U004219, 0197U003102 , R & D reports Title The investigation of intracellular regulation mechanisms of functional state of hepato-biliary system popup.stage_title Head Kaplunenko Mykola Oleksijovych, Registration Date 19-03-2001 Organization Taras Shevchenko Kiev University popup.description2 It has been shown by experiments carried on white rats in vivo and on isolated perfused liver that in the regulation of the functional states of hepatobiliary system the edogenious regulatory substances (bile acids, opioid peptides, tachykinines, vitamin E) take an essential part. The empact of the mentioned substances on the liver cells is performed under the condition of their interaction with plasma membrane as well as with the functioning of cell nuclei and mitochondria, particular with their effect on RNA and DNA synthesis. Molecular mechanism of their activity is closely connected with second messengers. Product Description popup.authors popup.nrat_date 2020-04-02 Close