Registration Number
0124U004351,
(
0224U032933
0225U004117
)
R & D request
Title
Elucidation of functional relationships between isoforms of estrogen receptor ERα and isoforms of ribosomal protein kinase S6 (S6K1) in human breast carcinoma cells of different molecular subtypes
Head
Filonenko Valerii V., Доктор біологічних наук
Registration Date
09-10-2024
Organization
Institute of Molecular Biology and Genetics of NAS of Ukraine
popup.description1
The goal of the project is to determine the molecular regulatory relationships between isoforms of the estrogen receptor ERα and S6K1 kinase in human breast carcinoma cells of different molecular subtypes at the levels of regulation of their expression and activity and evaluate their role in the regulation of the transcriptome of genes associated with tumor progression, manifestations of key features of malignant cells and the effectiveness of tumor formation and metastases in model animals
popup.nrat_date
2024-12-09
