Registration Number
0126U004259,
(
0226U004541
0226U004543
0226U004545
)
R & D request
Title
Dynamic structure of nucleic acids and the mechanisms of their interactions with biologically active substances
Head
Horb Leonid H., Доктор хімічних наук
Registration Date
01-07-2026
Organization
Institute of Molecular Biology and Genetics of NAS of Ukraine
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1. Study the features of proton transfer from cytosine to guanine in a mini-helix with the structure dG5∙dC5.
2. Determine the stability of complexes obtained by high-throughput virtual screening and evaluate their energy parameters.
3. Conduct a large-scale study of the secondary structure of the HIV-1 gene region containing the PBS site in genomes of different subtypes.
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2026-07-01